Trials brief: semaglutide 44-week Phase 3 posts -12.2%, Roche files amylin-incretin combo, Amgen expands AMG 133

· Trials · Trials Desk

NCT06041217 published full Phase 3 results for semaglutide in obesity (mean -12.2% body weight at week 44, 80.5% achieved ≥5%). Roche registered a Phase 2 of petrelintide + enicepatide; Altimmune's pemvidutide NASH Phase 2 marked completed; Amgen's maridebart cafraglutide expanded into ASCVD, HFpEF, and OSA Phase 3.

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